Biography:

One of their most recent publications is Acid-free, organocatalytic acetalization. Which was published in journal Tetrahedron.

More information about Mike Kotke research including statistics on their citations can be found on their Copernicus Academic profile page.

Mike Kotke's Articles: (1)

Acid-free, organocatalytic acetalization

AbstractThe acid-free, organocatalytic acetalization of various aldehydes and ketones with N,N′-bis[3,5-bis(trifluoromethyl)phenyl]thiourea is presented. The neutral, double hydrogen bonding thiourea catalyst can be used at very low loadings of 0.01–1 mol% at room temperature to furnish the respective acetals in 65–99% yield at turnover frequencies around 600 h−1. Acid-labile TBDMS-protected as well as unsaturated aldehydes can be converted efficiently into their acetals utilizing this very mild and highly practical method.

Advertisement
Join Copernicus Academic and get access to over 12 million papers authored by 7+ million academics.
Join for free!

Contact us