Biography:

In the past Yuhua Cao has collaborated on articles with Yang Wang and Xiaolong Tu. One of their most recent publications is Determination of puerarin and daidzein in Puerariae radix and its medicinal preparations by micellar electrokinetic capillary chromatography with electrochemical detection. Which was published in journal Analytica Chimica Acta.

More information about Yuhua Cao research including statistics on their citations can be found on their Copernicus Academic profile page.

Yuhua Cao's Articles: (16)

Determination of puerarin and daidzein in Puerariae radix and its medicinal preparations by micellar electrokinetic capillary chromatography with electrochemical detection

AbstractThe use of micellar electrokinetic capillary chromatography (MECC) with electrochemical detection is described for the determination of puerarin and daidzein in Puerariae radix and its medicinal preparations. Operated in a wall-jet configuration, a 300 μm diameter carbon-disk electrode was used as the working electrode, which exhibits good responses at +900 mV (versus SCE) for the two analytes. Under the optimum conditions, the analytes were base-line separated within 11 min in a sodium dodecyl sulphate—borax (pH 7.8) running buffer, and excellent linearity was obtained in the concentration range from 5.0×10−4 to 5.0×10−6 mol/l. The detection limit (S/N=3) was 6×10−7 and 1.1×10−6 mol/l for puerarin and daidzein, respectively. This work provides a useful method for the analysis of traditional Chinese medicines.

Electrochemical sensor for parabens based on molecular imprinting polymers with dual-templates

AbstractA selective, sensitive, rapid and reliable method based on molecularly imprinted polymers (MIPs) with dual templates to determine total content of parabens in cosmetics was developed. With methylparaben (MP) and propylparaben (PP) as dual-templates, methacrylic acid (MAA) as a functional monomer and tripropylene glycol diacrylate (TPGDA) as a cross-linker, MIPs film on a glassy carbon electrode was constructed as paraben sensor. At oxidation potential of 0.94 V (vs. SCE), the peak currents on the MIPs sensor were proportional to the concentration of parabens with square wave voltammetry. As the ratio of MP to PP in the MIPs was 1:1.25, the regression equations for four parabens were almost the same. The linear range was 20–100 μM for MP and EP, 5–100 μM for PP, and 5–80 μM for BP, with detection limit of 0.4 μM for MP and EP, 0.2 μM for the others. The total content of parabens could be calculated according to the average of these four regress equations. At least 10 times of structural analogs, such as p-hydroxybenzoic acid, p-aminobenzoic acid and phenol would not interfere with the determination of parabens. Nonanalogous coexistences such as vitamin C had no response on the sensor at all. Rapid response of the MIPs sensor was obtained within 1 min. MIPs sensor had been used to determine total content of parabens in cosmetic samples with recoveries between 98.7% and 101.8%. It reveals that the MIPs sensor with multi-templates has a potential to determine the total content of a group of homologous compounds.

Efficient cancer ablation by combined photothermal and enhanced chemo-therapy based on carbon nanoparticles/[email protected]2 nanocomposites

AbstractThe combination of different treatments in cancer therapy has drawn massive attention in the last decades due to its superior anticancer ability to single treatment. One of the most useful strategies to achieve this purpose is to design and construct efficient multifunctional nanoplatforms. Here we report our effort in development of carbon nanoparticles/[email protected]2 nanocomposites and their application for combined photothermal and chemo-therapy in cancer ablation. The nanocomposites are obtained via reverse microemulsion method with controlled size and high drug loading ratio. These nanocomposites possess high heat-generating ability, pH responsive drug delivery, and heat-induced high drug release as well. In vitro experiment reveals that the combined photothermal and chemo-therapy exhibits much higher toxicity to 4T1 cells than photothermal therapy or chemotherapy alone. In vivo experiment reveals that compared with single treatment, the combined photothermal and chemo-therapy can effectively inhibit tumor growth and destroy it eventually without cancer recurrence. The current research demonstrates that carbon nanoparticles/[email protected]2 nanocomposites can be used as an efficient nanoplatform for combined cancer photothermal and chemo-therapy.

Short communicationDetermination of active ingredients of Rhododendron dauricum L. by capillary electrophoresis with electrochemical detection

AbstractHigh-performance capillary electrophoresis with electrochemical detection was employed to analyse active ingredients of Rhododendron dauricum L., an important crude herb frequently used in Chinese medicines. Farrerol, quercetin, syringic acid, vanillic acid, 4-hydroxybenzoic acid, protocatechuic acid are major important active ingredients. Operated in a wall-jet configuration, a 300-μm diameter carbon-disk electrode was used as the working electrode, which exhibits a good response at +950 mV (vs. saturated calomel electrodes) for six analytes. Under the optimum conditions, the analytes were baseline separated within 16 min in a borax buffer (pH 8.7). Notably, excellent linearity was obtained over two orders of magnitude with detection limits (S/N=3) ranged from 9·10−7 to 3.0·10−6 M for all analytes. This method was successfully used in the analysis of Rhododendron dauricum L. with relatively simple extraction procedures, and the assay results were satisfactory.

Vesicles formed by mixed catanionic surfactants as novel pseudostationary phase in electrokinetic chromatography

Highlights•A novel vesicle system formed by catanionic surfactants C8NE3Br/SDBS was developed as PSP in EKC.•C8NE3Br and SDBS could be mixed at any proportion without any agglomeration phenomena.•Eight kinds of corticosteroids with extremely similar molecular structures were separated completely using C8NE3Br/SDBS vesicle as PSP.•Compared with microemulsion modified with IL and polymeric micelle, the vesicle PSP had better separation performances.

Rapid analysis of water- and fat-soluble vitamins by electrokinetic chromatography with polymeric micelle as pseudostationary phase

Highlights•A novel polymeric micelle with high hydrophilic monomer ratio was used as PSP in EKC.•Organic solvents affected microstructure of the polymeric micelle.•11 kinds of fat- and water-soluble vitamins were simultaneously separated in 13 min.

Regular ArticleFabrication of iron-doped titanium dioxide quantum dots/molybdenum disulfide nanoflower for ethanol gas sensing

AbstractIn this paper, a high-performance ethanol sensor based on iron (Fe)-doped titanium dioxide (TiO2)/molybdenum disulfide (MoS2) nanocomposite was demonstrated. Flower-like MoS2 and Fe-TiO2 quantum dots (QDs) were synthesized by a facile hydrothermal route, and the Fe-TiO2/MoS2 composite was prepared via layer-by-layer (LbL) self-assembly technique. The Fe-TiO2/MoS2 film sensor was fabricated on a flame resistant (FR-4) epoxy substrate with interdigital electrodes. The microstructure, elementary composition, and morphology of the as-prepared samples were fully characterized by X-ray diffraction (XRD), energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), transmission electron microscope (TEM), and X-ray photoelectron spectroscopy (XPS). The gas sensing properties of the Fe-TiO2/MoS2 film sensor were determined at room temperature upon exposure to different concentration of ethanol gas. The experimental results illustrated that high response, short response/recovery time, stable repeatability, excellent selectivity long-term stability, and a detection limit of low ppb level was achieved by the Fe-TiO2/MoS2 sensor. The underlying sensing mechanism of the Fe-TiO2/MoS2 sensor toward ethanol is explored through systematically experimental investigation combining with first-principle density-functional theory (DFT) simulations. The enhanced ethanol sensing properties were ascribed to the Fe3+ ion doping, and p-n heterojunctions created at interfaces of n-type Fe-TiO2 and p-type MoS2.

Study on sugar profile of rice during ageing by capillary electrophoresis with electrochemical detection

AbstractA simple, reliable and reproducible method based on capillary electrophoresis with electrochemical detection, for the determination of sucrose, maltose, glucose and fructose in rice flour was described in this work. Operated in a wall-jet configuration, a 140 μm diameter copper-disk electrode was used as working electrode, which exhibits good response at +650 mV (vs. SCE) for sucrose, maltose, glucose and fructose. Under the optimum conditions, four analytes in 50 mmol/l sodium hydroxide buffer were base-line separated within 15 min. The response was linear over two orders of magnitude, and the detection limit (S/N=3) is 9 × 10−7 g/l, 1.4 × 10−6 g/l, 6 × 10−7 g/l and 1.3 × 10−7 g/l for sucrose, maltose, glucose and fructose, respectively. With this method, a sugar profile study of rice flour was conducted to determine changes produced during ageing. It is observed that there were decreases in the sucrose and maltose contents, and increases in glucose and fructose contents in rice during storage.

Original ArticleDetermination of Myo-inositol and d-chiro-inositol in black rice bran by capillary electrophoresis with electrochemical detection

AbstractA high-performance capillary electrophoresis (CE) method with electrochemical detection (ED) is developed for simultaneous determination of myo-inositol and d-chiro-inositol in black rice bran in this work. A 140 μm diameter copper-disk electrode operated in a wall-jet configuration, which exhibited good response at +0.65 V (relative to the saturated calomel electrode (SCE)) for the two analytes in 50 mm sodium hydroxide solution, was used as working electrode. The optimum conditions for determination was optimized with regard to the potential applied to the working electrode, concentration of the running buffer, separation voltage and injection time. The analytes were separated within 20 min. Excellent linearity was obtained in the concentration range from 1.0×10−6 to 1.0×10−4 g/ml for both analytes. The detection limit (S/N=3) was 5.3×10−7 and 7.3×10−7 g/ml for myo-inositol and d-chiro-inositol, respectively. The work provides a useful method for the analysis of myo-inositol and d-chiro-inositol in black rice bran.

Carbon monoxide gas sensing at room temperature using copper oxide-decorated graphene hybrid nanocomposite prepared by layer-by-layer self-assembly

Highlights•Copper oxide-decorated graphene-based sensor was fabricated by layer-by-layer (LbL) self-assembly route.•Sensing properties of copper oxide/graphene composite toward carbon monoxide gas were investigated.•The sensor exhibited high response, good reversibility, selectivity and repeatability for carbon monoxide gas sensing.

Humidity-sensing performance of layer-by-layer self-assembled tungsten disulfide/tin dioxide nanocomposite

Highlights•WS2/SnO2 nanocomposite was fabricated by layer-by-layer (LbL) self-assembly route.•Characterization and humidity sensing properties of WS2/SnO2 nanocomposite were investigated.•The WS2/SnO2 sensor exhibited the unparalleled response and sensitivity toward humidity.

Flexible integrated black phosphorus sensor arrays for high performance ion sensing

Highlights•FIBA realized multiplexed trace ion detection with excellent selectivity.•Small strain variation resulted in 175% enhancement of ion sensitivity.•FIBA exhibited the ability of monitoring target ions in real solution samples.

Cobalt-doped indium oxide/molybdenum disulfide ternary nanocomposite toward carbon monoxide gas sensing

Highlights•CoIn2O3/MoS2 nanocomposite was fabricated by layer-by-layer self-assembly technique.•CO gas sensing properties of CoIn2O3/MoS2 nanocomposite film sensor was investigated.•The sensing mechanism of CoIn2O3/MoS2 sensor was discussed by combining experiments with DFT simulation.

Electrochemical sensor based on molecular imprinting by photo-sensitive polymers

AbstractA novel voltammetric sensor based on molecularly imprinted polymers (MIPs) by a kind of photo-sensitive functional polymer was developed for determination of glucose in this work. Without the cross-linker and the initiator, a MIPs film on the surface of a gold electrode was easily formed by in-situ cross-link within 10 min under UV light irradiation. In alkaline medium, electrochemical oxidation behaviors of glucose on the MIPs sensor, as well as on a bare gold electrode have been investigated with square wave voltammetry. At oxidation potential of −0.50 V (vs. SCE), the peak currents on the MIPs sensor were proportional to the concentration of glucose in the range of 5.0–120 μM with the detection limit of 0.2 μg ml−1 (S/N = 3), whereas the extremely small responses of the control electrode were observed and independent of the analyte concentration. MIPs sensor displayed specific selectivity toward glucose in comparison to structurally similar analogues. The selective coefficient of glucose MIPs sensor with respect to maltose, arabinose and mannose was 9.17, 1.51 and 1.25, respectively. Fructose and inositol would not interfere with the determination of glucose because they could not be electrochemically oxidized at the potential of −0.50 V. Relative rapid response of the MIPs sensor was obtained within 7 min, and the RSD of peak currents was 5.0% (n = 5). MIPs sensor was applied to determine glucose in the simulative blood serum samples, the average recoveries was 92.6%. The experimental results showed that the sensor for glucose, based on MIPs by photo-sensitive polymers, was simpler to construct and operate, and provided an adequate sensitivity, good repeatability and accuracy and acceptable selectivity.

Short communicationElectrochemical sensor based on magnetic molecularly imprinted nanoparticles at surfactant modified magnetic electrode for determination of bisphenol A

Highlights•MMIP NPs had high saturation magnetization, regular sphere and monodispersity.•Magnetic electrode and MMIPs NPs were integrated to prepare MIPs sensor.•CTAB enhances spreadability, sensitivity and anti-fouling.•A stable, sensitive and selective MIPs sensor was constructed to determine BPA.

The Industrial Design Education Based on the Lifecycle Design

AbstractThis article from the industrial design education erted life cycle of design idea, and expounds the necessity about industrial design specific course life cycle design teaching practice and result, the paper puts forward the future industrial design education should strengthen the life cycle in the design of the ideas and methods.

Advertisement
Join Copernicus Academic and get access to over 12 million papers authored by 7+ million academics.
Join for free!

Contact us