Biography:

In the past Kevin O. Leslie has collaborated on articles with Diana N. Ionescu and Wesley S. Hilger. One of their most recent publications is 3 - A Pattern-Based Approach to Diagnosis. Which was published in journal .

More information about Kevin O. Leslie research including statistics on their citations can be found on their Copernicus Academic profile page.

Kevin O. Leslie's Articles: (4)

1 - Lung Anatomy

AbstractThe microanatomy of the lung holds the key to understanding lung pathology. Unfortunately this complex organ poses particular challenges for two-dimensional analysis under the microscope. From embryology to differentiated cellular morphology, this introductory chapter describes the primary histologic lobular landmarks and couples these with their respective functional components. Together these provide a foundation for understanding the relationship between location of disease and the clinical/radiologic consequences that result.

Transactions from the Thirty-Second Annual Scientific Meeting of the Society of Gynecologic SurgeonsHistological and biomechanical evaluation of implanted graft materials in a rabbit vaginal and abdominal model

ObjectiveThe objective of the study was to describe the histologic and biomechanical changes of implanted dermal collagen graft materials.Study designTwenty rabbits were randomized into 2 groups (6 and 12 weeks, respectively). Each rabbit had 4 graft segments (human dermis, porcine dermis, porcine collagen-coated polypropylene mesh, and autologous fascia) randomly implanted into the abdomen and the vagina. Biomechanical testing and histologic analysis was performed after recovery of graft segments.ResultsDermal graft segments showed a marked decrease in ultimate strength (84% to 86%) and elastic modulus (73% to 82%) that was significantly different from the decrease seen in autologous fascia or coated synthetic mesh (P < .0008 and P < .0001, respectively). The decrease in ultimate strength was associated with vaginal implantation (P = .057). Dermal graft materials had moderate inflammation and minimal collagen infiltration.ConclusionThe mechanical properties of dermal graft materials decline after implantation. Vaginal implantation may cause a different tissue response to graft material than abdominal implantation. Dermal graft material caused moderate inflammation and minimal collagen ingrowth remote from implantation.

Review ArticleUterine Smooth-Muscle Tumors with Unusual Growth Patterns

AbstractUterine smooth-muscle tumors with unusual growth patterns include a variety of neoplastic lesions characterized histologically by their similarity to adult smooth muscle tissue. The 3 primary neoplasms are intravenous leiomyomatosis, benign metastasizing leiomyoma, and leiomyomatosis peritonealis disseminata. We present a review of the recent literature along with the clinical and pathologic features of 5 illustrative cases from Mayo Clinic Arizona, Scottsdale.

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