AbstractAngiotensin-converting enzyme inhibitors slow the progression of left ventricular dysfunction in several clinical settings, and may protect cardiotoxicity induced by chemotherapy. There has been recent suggestions that there is a potential cardioprotective effect, especially with enalapril. Angiotensin II receptor blockers are a crucial drug in hypertension treatment, especially if there is any kind of intolerance to angiotensin-converting enzyme inhibitors. Its angiotensin-inhibiting effect may be protective.