Biography:

In the past David L. Bolender has collaborated on articles with Nighat P. Kokan-Moore. One of their most recent publications is Brief noteSecretion of inhibin βA by endoderm cultured from early embryonic chicken☆. Which was published in journal Developmental Biology.

More information about David L. Bolender research including statistics on their citations can be found on their Copernicus Academic profile page.

David L. Bolender's Articles: (3)

Brief noteSecretion of inhibin βA by endoderm cultured from early embryonic chicken☆

AbstractAlthough several reports have indicated a role for endoderm in the regulation of heart development, the mechanism remains unknown. To begin characterization of endoderm-secreted proteins, explants from postgastrulation (Hamburger-Hamilton stage 5/6–8 chicken embryos were cultured in defined medium. Fluorography of SDS-PAGE gels revealed a pattern of synthesized, secreted proteins that was independent of time in culture or embryonic stage when explants were removed. Approximately 10 labeled bands were detected, the most prominent of which migrated at 17, 25, and 200 kDa. ELISA analysis revealed that while acidic and basic fibroblast growth factor-like antigens were barely detectable, fibronectin and inhibin βA were very reactive. Western blot analysis verified the presence of fibronectin and, most remarkably, inhibin βA, activin dimers of which have recently been implicated in Xenopus mesoderm induction (Smith, Price, Van Nimmen, and Huylebrock (1990). Nature 345, 729).

3 - Basic Embryology

No abstract

Advertisement
Join Copernicus Academic and get access to over 12 million papers authored by 7+ million academics.
Join for free!

Contact us