S.C. Chhabra's Articles: (3)
AbstractSixty-nine plants are listed, which are used by traditional healers in five regions of Eastern Tanzania, Coast, Dar es Salaam, Kilimanjaro, Morogoro and Tanga. For each species the botanical name, vernacular name, collection number, locality, habit, distribution and medicinal uses are given. Results of a literature survey on medicinal uses, isolated constituents, and pharmacological effects are also provided.
AbstractSixty-nine Angiosperms (Mimosaceae to Papilionaceae) are listed, which are used by traditional healers in five regions of Eastern Tanzania; namely, Coast, Dar es Salaam, Kilimanjaro, Morogoro and Tanga. For each species listed, the botanical name, vernacular name, collection number, locality, habit, distribution and medicinal uses are given. Additionally, information from the literature on medicinal uses, chemical constituents, and pharmacological effects are also provided.
AbstractThe organic extracts of leaves and roots of five plants used for treating malaria in Central, Nairobi and Rift Valley Provinces, Kenya were tested for brine shrimp lethality and in vitro antiplasmodial activity against chloroquine sensitive and resistant strains of Plasmodium falciparum. Of the plants tested, 60% were toxic to the brine shrimp (LC50<30 μg/ml) and eight out of ten plant parts (80%) showed in vitro antiplasmodial activity (IC50<50 μg/ml). Among the extracts screened, the leaves of Cyathula polcephala had the highest toxicity to the brine shrimp (LC50=2.9 μg/ml) while the leaves of Pentas longiflora had the best antiplasmodial activity (IC50=11.4 μg/ml). The plant extracts with low IC50 values are potential sources for novel antiplasmodial compounds.