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Entropy-driven reactions in living cells for assay let-7a microRNA

Kai Zhang - No affiliation found

2017/01/01 Full-length article DOI: 10.1016/j.aca.2016.10.034 Journal: Analytica Chimica Acta

Abstract:

Highlights•An enzyme-free amplification strategy for microRNA assay is reported.•This strategy is employed to image miRNA in single cells by using entropy-driven reaction.•The method provides a high sensitivity with a detection limit of 0.27 pM of Let-7a.