NoteIrrelevance of growth phase with respect to the Bay n 7133 and ICI 153,066 susceptibilities of Candida albicans
Review articleOpen access
Abstract:

AbstractMiconazole at 10−5–10−4 M can kill Candidaalbicans in the logarithmic phase, but ketoconazole, the only established oral antifungal azole, cannot. Lethal potential in relation to growth phase was studied with Bay n 7133 and ICI 153,066, two recently developed oral triazoles. Each was strictly fungistatic regardless of phase of growth and was almost identical in effect to ketoconazole.

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