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Vitamin B12 deficiency and glutathione in the erythrocytes and livers of chicks

Jeng M. Hsu - No affiliation found

1959/09/01 Full-length article DOI: 10.1016/0003-9861(59)90549-1 Journal: Archives of Biochemistry and Biophysics

Abstract:

AbstractThe influence of vitamin B12 on the levels of erythrocyte and hepatic GSH in chicks on various diets have been studied.An increase in erythrocyte GSH was found in chicks receiving a high-fat diet supplemented with B12 (100 μg./kg.) and a methionine-deficient diet supplemented with B12 (50 μg/kg.) alone, or with the combination of methionine and B12.The addition of vitamin B12 (10 μg./kg.) to a high-protein diet did not change the erythrocyte GSH level.Vitamin B12 had no effect on hepatic GSH content under the conditions studied.