ReviewEnzyme-catalyzed oligosaccharide synthesis☆
Review articleOpen access
1992/05/01 Review article DOI: 10.1016/0003-2697(92)90099-S
Journal: Analytical Biochemistry
AbstractCell-surface carbohydrates and their conjugates are involved in many types of molecular recognition. This review describes recent developments in enzyme-catalyzed oligosaccharide synthesis, with particular focus on glycosyltransferase and glycosidase reactions. With the increasing availability of glycosyltransferases via recombinant DNA technology, glycosyltransferase-catalyzed glycosylation with in situ regeneration of sugar nucleotides appears to be the most effective method for large-scale stereocontrolled oligosaccharide synthesis.
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