ResourceFlexible Backbone Assembly and Refinement of Symmetrical Homomeric Complexes
Review articleOpen access
Abstract:

Highlights•SymDock2 is an algorithm to assemble symmetric protein structures from monomers•Coarse-grained score function discriminates near-native conformations•Flexible-backbone refinement is necessary to create realistic all-atom models•Results improve 5-fold and outperform other symmetric docking algorithms

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