PreviewXylosyltransferase 1 and the GAG Attachment Site
Review articleOpen access
Yanlei Yu - No affiliation found
2018/06/05 Short review DOI: 10.1016/j.str.2018.05.011
Xylosyltransferase initiates glycosaminoglycan synthesis on the proteoglycan core protein. In this issue of Structure, Briggs and Hohenester (2018) determined the crystal structure of xylosyltransferase 1 and its structure in ternary complex with UDP-xylose donor and peptide acceptors, providing a mechanistic insight into the role of xylosyltransferase for glycosaminoglycan site selection.
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