ReviewHIV-2: the forgotten AIDS virus
Review articleOpen access
2008/12/01 Review article DOI: 10.1016/j.tim.2008.09.003
Journal: Trends in Microbiology
HIV type 2 (HIV-2), a closely related retrovirus discovered a few years after HIV type 1, causes AIDS in only a minority of infected individuals. Determining why HIV-2 causes asymptomatic infection in most patients could further our understanding of HIV immunopathogenesis. Studies to date have suggested that both enhanced immune responses and lower viral replication could play a role. We summarize the important findings to date and highlight areas that warrant further exploration.
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