Korean mistletoe lectin promotes proliferation and invasion of trophoblast cells through regulation of Akt signaling
Review articleOpen access
Abstract:

Highlights•We analyzed the effect of VCA on proliferation and invasion in trophoblast.•Cell proliferations of trophoblast were increased at low concentration of VCA.•Low concentration of VCA increases MMP-2 expression in trophoblast.•The expressions of integrin subunits α5 and β1 were increased at 10 pg/ml of VCA.•VCA promotes invasion ability of trophoblast via the Akt signaling.

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