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Environmental enrichment may protect against neural and behavioural damage caused by withdrawal from chronic alcohol intake

Manoel Jorge Nobre - No affiliation found

2016/12/01 Full-length article DOI: 10.1016/j.ijdevneu.2016.09.003 Journal: International Journal of Developmental Neuroscience

Abstract:

Highlights•A role for environmental enrichment (EE) on alcohol intake is suggested.•EE has a protective role in the mPFC neurons and motivation for alcohol intake.•This effect is dependent from whether the animals were reared grouped or isolated.•EE has a protective effect on neural maintenance even in previously isolated rats.•For alcohol intake, isolation is a strong stressor from which EE has no effect.