Systematic or Meta-analysis StudiesManagement of non-metastatic castrate-resistant prostate cancer: A systematic review
Review articleOpen access

Highlights•nmCRPC is a heterogeneous stage of prostate cancer for which the challenge is to delay the onset of metastasis.•Until recently, few evidences were available to orient clinicians in the choice of treatment modalities.•Recent results obtained with next generation antiandrogen therapy demonstrate for the first time a survival benefit in this setting and will modify the management of nmCRPC.•New imaging technics will help improving diagnosis of prostate cancer and thus aid in determining the best treatment option.

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