Five-year outcome and predictors of success after second-generation cryoballoon ablation for treatment of symptomatic atrial fibrillation
Review articleOpen access

Highlights•We present the first reportof 5-year outcome after pulmoary vein isolation using the second-generationcryoballoon.•After a single procedure,59.0% of the patients maintained sinus rhythm during long-term follow-up.•Patients with a left atrial area ≤21 cm2 without diabetes showed the best outcome.•Ongoing surveillance is warranted, even if pulmonary vein isolation is deemed initially successful.

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