The attenuating effects of 1,2,3,4,6 penta-O-galloyl-β-d-glucose on pro-inflammatory responses of LPS/IFNγ-activated BV-2 microglial cells through NFƙB and MAPK signaling pathways
Review articleOpen access

Highlights•PGG modulated the expression of genes and proteins involved in the NFƙB and MAP kinase signaling pathways.•PGG down-regulated CDK2, CHUK, IRAK1, and NFƙB1 expression in the transcriptional and protein level.•PGG effect may be modulating the activation of transcription factors responsible for pro-inflammatory cytokines production.

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