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Research paperDifferential expression of type I interferon mRNA and protein levels induced by virulent Marek’s disease virus infection in chickens

Guo-rong Sun - No affiliation found

2019/06/01 Full-length article DOI: 10.1016/j.vetimm.2019.04.010 Journal: Veterinary Immunology and Immunopathology

Abstract:

Highlights•We studied IFN mRNA/protein expression in MDV-infected hosts for the first time.•MDV inhibited type Ⅰ IFN expression in the thymus and bursa of infected chickens.•Inhibition of type I IFNs by MDV strains of varying pathogenicity differed.