Research paperEffort-based decision-making is affected by overweight/obesity in major depressive disorder
Review articleOpen access

Highlights•Abnormalities in reward are core features of major depressive disorder (MDD).•Overweight/obesity (OW) is independently associated with reward disturbances.•We investigated effort-based decision making in individuals with MDD and OW.•OW significantly moderated the association between MDD and lower effort behavior.•Body mass index was more strongly associated with effort than depressive symptoms.

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