ReviewThe theory of bipolar disorder as an illness of accelerated aging: Implications for clinical care and research
Review articleOpen access
Abstract:

Highlights•Pathophysiological changes observed in BD converge on a model of premature aging.•Individuals with BD present high rates of age related medical illnesses.•Dysregulation in immune system and neurotrophins are present in both conditions.•Recognition of BD as an accelerated aging disease opens a new avenue of investigation.

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