Secretory antibody response to haemagglutinin of influenza virus A/Swine and A/Victoria in humans after administration of split and whole-virion vaccine
Review articleOpen access

After vaccination of 31 children with the influenza split vaccine (A/Swine) no nasal secretory antibodies against haemagglutinin were demonstrated in any case.After vaccination of adults with whole virus bivaccine containing A/Swine (HswN1) and A/Port Chalmers (H3N2) viruses, the presence of secretory antibodies against haemagglutinin of the virus A/Swine was demonstrated in 8% of the younger (18–40 years) and 42% of the older (42–80 years) subjects, antibodies against haemagglutinin of the A/Victoria (H3N2) virus being demonstrated in 58% of the younger and 12% of the older persons.

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