ReviewReviewing the molecular mechanisms which increase endometrial cancer (EC) risk in women with polycystic ovarian syndrome (PCOS): Time for paradigm shift?
Review articleOpen access
Abstract:

Highlights•The molecular mechanisms linking PCOS and endometrial cancer are inconclusive.•Hyperinsulinaemia and hyperestrogenism herald to genes over-expression in the pathogenesis of both PCOS and endometrial cancer.•A paradigm shift into ‘-omics’ research would yield a better understanding of the linkage.

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