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An efficient synthesis of thiazolo[3,2-a]pyrimidinones

Nadia M. Ahmad - No affiliation found

2010/06/23 Short communication DOI: 10.1016/j.tetlet.2010.04.052 Journal: Tetrahedron Letters

Abstract:

AbstractA series of thiazolo[3,2-a]pyrimidinones was synthesised in a two-step procedure, using Eaton’s reagent to effect cyclisation of 2-aminothiazoles. The use of relatively low temperatures, facile product isolation and short reaction times make this cyclisation procedure a particularly attractive option over more conventional methods.