Total synthesis of thienamycin analogs—III : Syntheses of 2-aryl and 2-heteroaryl analogs of thienamycin
Review articleOpen access
L.D. Cama - No affiliation found
1983/01/01 Full-length article DOI: 10.1016/S0040-4020(01)92147-7
Journal: Tetrahedron
Abstract:
AbstractThe total syntheses of 2-aryl and 2-heteroaryl carbapen-2-em-3-carboxylic acids with and without a 6-hydroxyethyl side chain, using a Wittig cyclization for formation of the bicyclic ring system is described. Antibacterial activity of the compounds synthesized is discussed.
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