Radical cyclization strategies to terpenoids; syntheses of (±)-β-cuparenone, (±)-laurene and epilaurenes
Review articleOpen access
Abstract:

AbstractRadical cyclization of the bromide 8, obtained in 5 steps from the ketone 9, furnished exclusively 14via 6-endo trig cyclization with out any observable amount of 5-exo trig product 1. 5-Exo dig radical cyclizatlon of the bromo acetate 23, prepared from 18via the aldehyde 21, followed by routine transformations furnished the cyclopentenone 26, an immediate precursor to β-cuparenone (2). Similarly, total synthesis of laurenes 4 and 5 was achieved via the 5-exo dig radical cyclization of the xanthate 28, obtained from the aldehyde 21.

Request full text

References (0)

Cited By (0)

No reference data.
No citation data.
Advertisement
Join Copernicus Academic and get access to over 12 million papers authored by 7+ million academics.
Join for free!