Invited reviewInvolvement of glutamatergic and GABAergic systems in nicotine dependence: Implications for novel pharmacotherapies for smoking cessation
Review articleOpen access

Highlights•Blockade of glutamatergic transmission inhibited nicotine reward.•Facilitation of GABAergic transmission inhibited nicotine reward.•Blockade of glutamatergic transmission inhibited nicotine-seeking behavior.•Facilitation of GABAergic transmission inhibited nicotine-seeking behavior.•Glutamatergic and GABAergic medications may be promising for smoking cessation.

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