Clinical studyClinical value of serum polysaccharide determinations by the tryptophane-perchloric acid reaction
Review articleOpen access

Abstract1.1. Seibert's modification of the tryptophane-perchloric acid reaction has been employed to determine serum polysaccharide levels in a survey of general hospital patients.2.2. Elevation of the serum polysaccharides was most marked and frequent in patients with neoplasms, chronic infections, hyperthyroidism and cardiovascular diseases. Abnormal values were less often observed in patients with acute infections, hepatic disease, rheumatic fever and miscellaneous disorders. Normal values were the rule in pregnancy.3.3. Serum polysaccharide elevation appears to reflect biochemical changes different from those measured by sedimentation rate and other routine laboratory studies.

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