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Platelet reactivity and coronary microvascular impairment after percutaneous revascularization in stable patients receiving clopidogrel or prasugrel

Fabio Mangiacapra - No affiliation found

2018/11/01 Full-length article DOI: 10.1016/j.atherosclerosis.2018.08.044 Journal: Atherosclerosis

Abstract:

Highlights•Prasugrel, compared with clopidogrel, attenuates peri-procedural increase in platelet reactivity.•A significant correlation exists between platelet reactivity and coronary microvascular function at the time of PCI.•The more profound platelet inhibition may contribute to the protective effect of prasugrel on coronary microcirculation.